Apoptosis Reagents and Kits
Cayman Chemical Z-YVAD-CMK (trifluoroacetate salt), Purity: ≥95%, 1 mg
An inhibitor of caspase-1 and caspase-3; reduces IL-1β and IL-18 secretion in isolated mouse peritoneal macrophages by cholesterol-treated rPLY at 30 µM; reduces caspase-3 activation by the EGF-like domain of tenascin-C in detached hSMCs in vitro; decreases cell death induced by the EGF-like domain of tenascin-C by 50% at 100 µM; completely inhibits cell death of hSMCs at 200-400 µM
Abcam Human PCBD1 knockout HEK-293T cell lysate.
Human PCBD1 knockout HEK-293T cell lysate.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Human PSIP1 (LEDGF) knockout HEK-293T cell lysate.
Human PSIP1 (LEDGF) knockout HEK-293T cell lysate.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Human ALDH2 knockout SW480 cell lysate.
Human ALDH2 knockout SW480 cell lysate.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Human JMJD6 knockout HEK-293T cell lysate.
Human JMJD6 knockout HEK-293T cell lysate.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Human FOXO3 (FOXO3A) knockout HEK-293T cell lysate.
Human FOXO3 (FOXO3A) knockout HEK-293T cell lysate.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Human RELB (Rel B) knockout HeLa cell lysate.
Human RELB (Rel B) knockout HeLa cell lysate.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Human PNP (Nucleoside phosphorylase) knockout HEK-293T cell lysate.
Human PNP (Nucleoside phosphorylase) knockout HEK-293T cell lysate.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Human MAP2K7 (MKK7) knockout A549 cell lysate.
Human MAP2K7 (MKK7) knockout A549 cell lysate.
The product is subject to the following: Abcam Restricted Use Statement
Apexbio Technology LLC Caspase-3-Fluoro-Assay-Kit
Caspase-3 Fluorometric Assay Kit is widely used in biomedical research to study cell apoptosis Originating from studies on apoptosis pathways this kit detects the activity of caspase-3 an enzyme playing a critical role in the execution phase of cell apoptosis It targets the cleavage of the specific substrate releasing a fluorescent reporter that allows quantification of enzyme activity This detection method is highly sensitive enabling the measurement of caspase activity in the nanomolar to low micromolar range Commonly applied in vitro it is essential for evaluating programmed cell death in various cell models including cancer and stem cells with applications extending to animal studies and drug screening Experimental concentrations typically depend on the specific research design providing flexibility in optimizing conditions for diverse experimental setups and requirements
Medchemexpress LLC HY-130250 5mg Medchemexpress, SR-4835 CAS:2387704-62-1 Purity:>98%
Medchemexpress, HY-130250 5mg SR-4835 CAS:2387704-62-1 SR-4835 is a potent, highly selective and ATP competitive dual inhibitor of CDK12/CDK13 (CDK12: IC50=99 nM, Kd=98 nM; CDK13: Kd=4.9 nM). SR-4835 acts in synergy with DNA-damaging chemotherapy and PARP inhibitors and provokes triple-negative breast cancer (TNBC) cell death. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
ABclonal Technology Caspase-7 Rabbit pAb
This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. The precursor of the encoded protein is cleaved by caspase 3 and 10, is activated upon cell death stimuli and induces apoptosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Abcam Human FTH1 knockout HEK-293T cell lysate.
Human FTH1 knockout HEK-293T cell lysate.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Human GRB2 knockout HCT116 cell lysate.
Human GRB2 knockout HCT116 cell lysate.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Human KRT8 (Cytokeratin 8) knockout HeLa cell lysate.
Human KRT8 (Cytokeratin 8) knockout HeLa cell lysate.
The product is subject to the following: Abcam Restricted Use Statement